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Clinical Trials

Last Updated 12/20/01

Information on Some Current Women's Health Research Studies at the University of Cincinnati
                                      

New Spermicide Study
Michael Thomas, MD., Professor of Obstetrics and Gynecology, and co director of the UC center for Reproductive Medicine Research, received a $421,000 grant from the National Institute of Health (NIH) to study a new spermicide. The purpose of this study is to compare a new spermicide with an over the counter spermicide. The spermicides will be used with a diaphragm. Products will be compared for effectiveness and side effects. Participants will be required to use this as their primary method of birth control. There will be 975 female subjects across the country taking part in this study. The study participation will last six menstrual cycles or approximately seven months. Age for woman in this clinical trial will be in the range of 18 and 40 years old. You should not participate in this study if you have a known allergy or sensitivity to spermicide gels or products containing latex. Women cannot participate in this research if they have used Depo-Provera in the past ten months, are pregnant or breastfeeding. Women should be generally healthy and not diagnosed with sexually transmitted diseases in the previous six months.

Participants will be compensated for their time.

For more information or to see if you qualify
for this study Please call: (513) 584-4100

 

Estrogen Study
Dr. Margery Gass Professor of Obstetrics & Gynecology & Dr. Jared Robins Assistant Professor of reproductive endocrinology and infertility are conducting a research study on a low dose of Cenestin, a synthetic conjugated estrogen, manufactured Duramed Pharmaceuticals Inc., for postmenopausal woman. Cenestin is approved by the Food and Drug Administration at dose levels of 0.625mg, 0.9mg, and 1.25 mg for the treatment of vasomotor symptoms in postmenopausal women. This research study will test lower dose of Cenestin 0.3 mg compared with placebo, to determine if prevention of calcium loss from bone can be achieved. In addition, the effects of Cenestin on the blood flow to the brain will be examined by ultrasound. There will be 124 postmenopausal women participating in this study. Participation will last approximately 12 month. Women in this study will be between 45 & 55 years old and have not had a period for 12 months.

Study participants may receive at no cost: bone density scans, lab tests, mammogram, Pap smear, and study medication.

Participants will be compensated for their time and travel.

For more information or to see if you qualify
for this study Please call: (513) 584-4100

Heating Pad Study
If you have pain associated with your period you may qualify for a UC study.

Dr. Michael A. Thomas, M.D., Associate Professor of Obstetrics and Gynecology and Director of the Center for Reproductive Health is conducting a study to determine how topical heat can decrease pain from menstrual periods. Women participating in the study will receive compensation for their time, which could last up to four hours. A heating pad will be placed on the abdominal area of the participants and skin sensors will be used to regulate the heating pad temperature. Doppler flow measurements using a trasvaginal ultrasound probe will take place during the study.

The purpose of this research study is to determine whether heat will open vessels and relieve pain. To participate, you must be 18-35 years old.

You should not participate in this study if you have taken a hormonal contraceptive pill eight weeks before the study, If you have used Depo-Provera within the last nine months, or if you are pregnant, lactating, or less than six months postpartum.

For more information or to see if you qualify
for this study Please call: (513) 584-4100

Emergency Contraception
If you find yourself without protection within the last three days you may qualify for a physician supervised study on the use of emergency contraceptives, sometimes called the “Morning After” pill. 

  • Compensation for Time & Travel 

To see if you may qualify please call 

Reproductive Medicine Research
University of Cincinnati Medical Center
(513) 543-6623

Hysterectomized Women
In the past seven years, between the ages of 35 and 60 years old are needed for an important research study on the effect of estrogen on the prevention of osteoporosis

 Study Participation may include at no cost:

  • Bone Density Scans
  • Lab Test
  • Mammogram, Pap smear and complete physical exam
  • Study Medication

You will be required to make at least 6 visits

  • Compensation for time and travel

To see if you qualify please call
(513) 584-4100 
Reproductive Medicine Research/University of Cincinnati Medical Center

Could you have Osteoporosis?
If you are a women at least 40 years old and past the change of life, you may qualify for a medical research study.  This research study will test two approved, marketed medications for the treatment of osteoporosis. Benefits of being a participant in this one-year study include study medication, study related check-ups, lab testing and bone density scan tests.

So if you’re a women at least 40 years old and past the change of life call today to get more information and to see if you may qualify.

 Please call Reproductive Medicine Research/University of Cincinnati Medical Center at (513) 584-4100.

 

Where you can find more Clinical Trials:

University of Cincinnati Office of Clinical Trials
231 Albert Sabin Way
Cincinnati, OH 45267-0559
Phone: (513) 558-3314
Fax: (513) 558-2661
Web site: http://www.clinicaltrials.uc.edu
Access the clinical trials web site to find clinical trials you may be interested in participating in. To find a clinical trial first select the medical category, example “psychiatry". There are current listings for binge eating, depression, panic disorders and others. Also see “Patient Resources” for information on what a clinical trial is, what the phases of trials are, and clinical trial terminology.

 UC Cancer Programs
Web site: http://uccancerprograms.uc.edu/ 
Phone: (513) 584-7698
This Web site contains a complete and current listing of all cancer related clinical trials at the University of Cincinnati Medical Center.

National Breast Cancer Coalition - The NBCC Foundation's Clinical Trials Project was developed to encourage and improve critical breast cancer clinical trials research, and increase access to high quality clinical trials for all breast cancer patients. They are helping to recruit for Genetech's Herceptin clinical trial for patients with advanced breast cancer, and also for the Avastin trial. [For information click on the NBCC link, then on "education and training" and "clinical trials". Use the NIH clinical trials link below, to find local sites.]

National Institutes of Health
ClinicalTrials.gov
The U.S. National Institutes of Health, National Library of Medicine, has developed ClinicalTrials.gov to provide patients, family members and members of the public current information about clinical research studies.
Website: http://clinicaltrials.gov

WOMANCANDO.ORG
Some Things Only a Woman Can Do
Society of Women's Health Research
A National Campaign to Educate Women about Medical Research
This site has links medical research study listings on the internet and answers your questions about medical research. This is also a place where you can learn what medical research terms mean. 
Web site: http://www.womancando.org

National Institute of Environmental Health Sciences
The Sister Study
A study to identify genetic and environmental risk factors for breast cancer by studying 50,000 women who have a sister who had breast cancer.
Web site: http://www.4sister.org